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Cytochrome P450 is a family of isozymes responsible for the biotransformation of several drugs. Drug metabolism via the cytochrome P450 system has emerged as an important determinant in the occurrence of several drug interactions that can result in drug toxicities, reduced pharmacological effect, and adverse drug reactions.

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Nomenclature. Genes encoding CYP enzymes, and the enzymes themselves, are designated with the root symbol CYP for the superfamily, followed by a number indicating the gene family, a capital letter indicating the subfamily, and another numeral for the individual gene.The convention is to italicise the name when referring to the gene. For example, CYP2E1 is the gene that encodes the enzyme ...

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The Michigan Legislature Website is a free service of the Legislative Service Bureau in cooperation with the Michigan Legislative Council, the Michigan House of Representatives, the Michigan Senate, and the Library of Michigan.

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Unlike cytochrome P450 oxidoreductase deficiency, 21-OHD is characterized by elevated serum concentrations of adrenal androgens. 3ß-hydroxysteroid dehydrogenase deficiency is a rare condition that can lead to ambiguous genitalia in both females and males.